VIDEO: AREDS vitamins may slow GA; C1q inhibitor shows visual acuity signal

CHICAGO — In this video from the AAO meeting, Joan W. Miller, MD, chair of ophthalmology at Mass Eye and Ear, discusses the role of AREDS vitamins in slowing the progression of geographic atrophy.

“That is something we hadn’t really thought was a benefit, but it may be that that also has a role,” she said.

In addition, she discussed data on a C1q inhibitor that failed to meet its primary endpoint but did show a visual acuity signal, which Miller called “intriguing.”

References:

• Keenan TD. The importance of the AREDS supplements in progression of geographic atrophy lesions. Presented at: American Academy of Ophthalmology meeting; Oct. 18-21, 2024; Chicago.
• Khurana RN, et al. Preservation of vision by ANX007: Clinical results and anatomical changes from the phase 2 ARCHER trial. Presented at: American Academy of Ophthalmology meeting; Oct. 18-21, 2024; Chicago.

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Healio Interviews

Disclosures:
Miller reports serving as a named inventor on patents and patent applications for ONL Therapeutics; serving as a consultant for ONL Therapeutics and Sumitomo Pharma Co.; serving in an advisory role for Drusolv Therapeutics; and receiving grant support from Lowy Medical Research Institute. Massachusetts Eye and Ear has a proprietary interest in photodynamic therapy and has received financial remuneration related to this technology. Miller reports receiving a share of the same in accordance with institutional guidelines.

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