Discussion/Takeaways:
- Drug induced retinopathies should not be overlooked in patients with nyctalopia.
- It is imperative to do an extended retinal examination of patients reporting visual distortions or difficulty in seeing in dim lighting even if VA is not reduced.
- Patients taking PPS should be monitored closely for retinal toxicity similar to patients taking Chloroquine/Hydroxychloroquine. Baseline testing at initiation of drug intake and then at least on an annual basis thereafter
- As eye-care providers we need to be aware of potential retinal toxicity of PPS and need to discuss with PCP and urologists regarding need for PPS for cystitis is worth the risks
- Peripapillary hypoAF is distinct to PPM. The density of abnormalities seen in FAF is higher in PPSM than in inherited maculopathies and PPM does not spare the fovea and is not associated with systemic muscle weakness as mitochondrial diseases can be.
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