This cross-sectional study investigates how published polygenic risk scores for primary open-angle glaucoma (POAG) perform in groups with African ancestry compared with European ancestry. … [Read more...] about Polygenic Risk Scores for POAG in Populations of African Descent
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Negative Treponemal Serologies in Syphilitic Panuveitis
This case report describes an HIV-positive patient with bilateral syphilitic panuveitis, for whom diagnosis was initially delayed by negative treponemal testing. … [Read more...] about Negative Treponemal Serologies in Syphilitic Panuveitis
Viral Meningoencephalitis and Bilateral Blurry Vision
A 20-year-old Chinese woman was experiencing fever, malaise, headache, nausea, vomiting, and neck stiffness for 2 weeks. Further examination revealed inflammation, vitritis and cystoid macular edema, tortuous dilatation of retinal venous vessels with fluorescence leakage, and hyperfluorescence in the optic disc. What would you do next? … [Read more...] about Viral Meningoencephalitis and Bilateral Blurry Vision
The role of the KEAP1-NRF2 signaling pathway in form deprivation myopia guinea pigs
In recent years, the global prevalence of myopia has reached an unprecedented level, especially in East Asia. Multitude of studies has shown that the etiology of myopia is complex. Some researchers have sugge... … [Read more...] about The role of the KEAP1-NRF2 signaling pathway in form deprivation myopia guinea pigs
A case of acute idiopathic maculopathy in both eyes with peripheral vascular occlusion
This study aimed to present a case of bilateral symmetric onset of acute idiopathic maculopathy after high fever with peripheral vascular occlusion. … [Read more...] about A case of acute idiopathic maculopathy in both eyes with peripheral vascular occlusion
VIDEO: Axpaxli may disrupt treatment paradigm for retinal vascular diseases
November 13, 2024 3 min watch NEW YORK — In this Healio Video Perspective from OSN New York, Sanjay Nayak, MBBS, PhD, of Ocular Therapeutix discusses Axpaxli for the treatment of retinal vascular diseases. According to Nayak, Axpaxli (axitinib intravitreal implant) is “a single injection, a single completely bioabsorbable hydrogel that … [Read more...] about VIDEO: Axpaxli may disrupt treatment paradigm for retinal vascular diseases
VIDEO: Oral Stargardt’s disease treatment focuses on reducing vitamin A dimerization
November 13, 2024 2 min watch CHICAGO — In this Healio Video Perspective from Eyecelerator@AAO, Michel Dahan, CEO of Alkeus Pharmaceuticals discusses ALK-001, the company’s oral therapy for the treatment of Stargardt’s disease and age-related macular degeneration. ALK-001 (gildeuretinol) is “a new chemical entity designed to lower dimerization in the retina and do so … [Read more...] about VIDEO: Oral Stargardt’s disease treatment focuses on reducing vitamin A dimerization
VIDEO: More durable retinal treatments can help improve clinical capacity, patient care
November 13, 2024 2 min watch BARCELONA, Spain – In this Healio Video Perspective from the Euretina congress, David Wong, MD, shares his thoughts on the advantages of new drugs for retinal conditions including age-related macular degeneration. Clinicians are facing “a tsunami of injections,” he said, because new options are now becoming available for retinal … [Read more...] about VIDEO: More durable retinal treatments can help improve clinical capacity, patient care
Atsena Therapeutics and Nippon Shinyaku enter exclusive license agreement for ATSN-101
Atsena Therapeutics Inc. and Nippon Shinyaku Co., Ltd. have entered into an exclusive license agreement for the commercialization of ATSN-101 in the United States and for the development and commercialization of ATSN-101 in Japan. This collaboration aims to advance ATSN-101, an investigational gene therapy for Leber congenital amaurosis (LCA) caused by biallelic mutations in … [Read more...] about Atsena Therapeutics and Nippon Shinyaku enter exclusive license agreement for ATSN-101
Study examines the use of AI–based detection of diabetic retinopathy in the US
A team of researchers recently conducted a cohort study to investigate the adoption of artificial intelligence (AI)-based diabetic retinopathy (DR) detection in US healthcare settings, highlighting both the promise and slow uptake of this technology.In the study, the researchers traced the use of Current Procedural Terminology code 92229, an AI-based screening reimbursement … [Read more...] about Study examines the use of AI–based detection of diabetic retinopathy in the US