The first patient has been successfully dosed in the phase I/IIa clinical trial of ABI-110, Avirmax Biopharma's first gene therapy drug for the treatment of wet age-related macular degeneration (AMD) including polypoidal choroidal vasculopathy (PCV).In the press release1, Shawn Liu, PhD, Chief Executive Officer of Avirmax Biopharma Inc. highlighted this step forward, saying, … [Read more...] about Avirmax Biopharma doses first patient in phase I/IIa clinical trial of ABI-110
News
Woman presents for second opinion regarding medication use
November 25, 2024 5 min read A 32-year-old woman was referred by the rheumatology service for a second opinion regarding high-risk medication use evaluation. The patient’s medical history was notable for systemic lupus erythematosus, complicated by lupus nephritis, as well as miscarriage at 11 weeks’ gestation. She never had ocular surgery … [Read more...] about Woman presents for second opinion regarding medication use
Take steps throughout surgical case to avoid postoperative ocular inflammation
November 25, 2024 3 min read Inflammation is associated with every surgical procedure. In most surgical specialties, postoperative inflammation is considered an expected part of the healing process. The associated discomfort and swelling are treated with cold compresses and oral analgesic medications, but the surgical site inflammation itself … [Read more...] about Take steps throughout surgical case to avoid postoperative ocular inflammation
Rising tide of ocular surface disease in young patients needs to be addressed
November 25, 2024 4 min read For many years, I have seen older patients with obvious meibomian gland dysfunction at the lid margin, often combined with blepharitis. Their gland openings are problematic, but when we do meibography, the internal glands are intact. Today, at least half of the patientswho come to me are younger than 50 years of age, and I have been seeing … [Read more...] about Rising tide of ocular surface disease in young patients needs to be addressed
Pearls for success with full-range diffractive IOLs
November 25, 2024 3 min read Over the course of the past decades, our IOL technology has continued to improve, particularly with the ability to address presbyopia. Today we are fortunate to have three FDA-approved diffractive IOL designs that provide a full range of uncorrected vision for our cataract surgery patients. With these new options, we anticipate a greater … [Read more...] about Pearls for success with full-range diffractive IOLs
Old habits die dry: Philosophical considerations of dry eye disease
November 25, 2024 4 min read Don’t try to convince yourself otherwise. We are all guilty. Much of our clinical practice of eye care is deeply entrenched in habit — and for good reason. Habits are what allow us to survive a busy day at the office. They are formed out of experience, intuition and maybe even a little bit of scientific evidence. … [Read more...] about Old habits die dry: Philosophical considerations of dry eye disease
My anti-inflammatory drug regimen
November 25, 2024 2 min read The goals of postoperative anti-inflammatory medications are to reduce pain, discomfort and inflammation and to prevent cystoid macular edema and prolonged or rebound iridocyclitis following cataract surgery. In addition to clinical efficacy, my regimen has several secondary objectives. I want it to be simple for patients to remember and … [Read more...] about My anti-inflammatory drug regimen
Intracameral antibiotic prophylaxis: Where do we stand?
November 25, 2024 6 min read Welcome to another edition of CEDARS/ASPENS Debates. CEDARS/ASPENS is a society of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology. Kenneth A. Beckman This month we are going to discuss the use of intracameral antibiotics in the course of cataract surgery as a prophylaxis … [Read more...] about Intracameral antibiotic prophylaxis: Where do we stand?
Be prepared for inflammation after cataract surgery
November 25, 2024 9 min read Inflammation is a common but treatable complication of cataract surgery. While surgeons have tools to handle this inflammation and potential consequences, patients who contend with it might not be happy with their recent procedure. When they experience pain, redness or blurred vision, John A. Hovanesian, MD, FACS, … [Read more...] about Be prepared for inflammation after cataract surgery
Back to basics part 4: Treatment 101
November 25, 2024 6 min read As promised, here is the fourth installment of the dry eye disease “Back to Basics” series requested by an audience member at a dinner presentation I gave last winter. In part 1, we took a look at normal tears, of which we have three types: baseline, psychic and reflex. Part 2 was snuck into the annual September column on the state of … [Read more...] about Back to basics part 4: Treatment 101