Curacle presented the results of its phase 2a clinical trial of CU06 for diabetic macular edema (DME) at the 4th Asia Retina Congress. This meeting is being held alongside the 2024 Annual Meeting of the Korean Retina Society in Seoul.The trial of this oral medication, which involved 67 DME patients in the US over a three-month period, showed improvements in best corrected … [Read more...] about Curacle presents results of its phase 2a clinical trial of CU06 for DME
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Gene therapy receives rare pediatric disease designation for inherited retinal dystrophy
December 20, 2024 1 min read The FDA granted rare pediatric disease designation for HORA-PDE6b, a gene therapy for patients with inherited retinal dystrophy caused by mutations of the PDE6B gene, according to a press release from eyeDNA Therapeutics. The AAV5-based gene therapy is designed to delay or halt retinal degeneration in PDE6B-deficient patients through … [Read more...] about Gene therapy receives rare pediatric disease designation for inherited retinal dystrophy
Efficacy of 4% tetracaine gel and lidocaine-prilocaine cream in reducing local anesthetic injection pain in upper eyelid blepharoplasty: a randomized, single-blinded, controlled trial
The injection of local anesthetics, an extremely painful procedure, leads to a reduction of patients’ acceptance. … [Read more...] about Efficacy of 4% tetracaine gel and lidocaine-prilocaine cream in reducing local anesthetic injection pain in upper eyelid blepharoplasty: a randomized, single-blinded, controlled trial
Comparison of efficacy and safety between gonioscopy-assisted transluminal trabeculotomy and trabeculectomy for primary open-angle glaucoma treatment: a retrospective cohort study
Trabeculectomy (TRAB) traditionally has been the gold-standard surgical treatment for primary open-angle glaucoma (POAG), while gonioscopy-assisted transluminal trabeculotomy (GATT) is an emerging minimally in... … [Read more...] about Comparison of efficacy and safety between gonioscopy-assisted transluminal trabeculotomy and trabeculectomy for primary open-angle glaucoma treatment: a retrospective cohort study
Analysis of topical conjunctival microbiotic cultures in patients treated with intravitreal injections using antibiotic prophylaxis with 0.3% ofloxacin eye drops
A total of 98 participants (50% men) were evaluated. Table 1 shows the gender, eye laterality, and number of applications by eye. For sex and laterality, the percentage was calculated in relation to the total number of participants. The male prevalence was 50%; both eyes of 50% of patients were included; and three or more applications were administered to both eyes in 80%. … [Read more...] about Analysis of topical conjunctival microbiotic cultures in patients treated with intravitreal injections using antibiotic prophylaxis with 0.3% ofloxacin eye drops
Clinical outcomes of two symmetrical Kera-rings implanted in grade three keratoconus: a retrospective nonrandomized study
To evaluate the clinical outcomes of implanting two symmetrical Kerarings via a femtosecond laser in grade three keratoconus. … [Read more...] about Clinical outcomes of two symmetrical Kera-rings implanted in grade three keratoconus: a retrospective nonrandomized study
Report details feasibility of whole eye transplant
December 19, 2024 1 min read Key takeaways: Globe and retinal perfusion were observed through fluorescein angiography. There was no evidence of acute rejection. A patient who underwent a combined whole eye and face transplant maintained globe and retinal perfusion as well as retinal response to light with no instance of acute rejection, according to a report in … [Read more...] about Report details feasibility of whole eye transplant
‘Catching up with reality’: Medical field recognizing the ongoing decline in men’s health
December 19, 2024 7 min read Key takeaways: Men face a higher risk for mortality than women in almost every phase of life. Healio spoke with experts to learn more about the decline in men’s health and what physicians can do to help. Men’s health has been declining for years in the United States, and health literacy may play an … [Read more...] about ‘Catching up with reality’: Medical field recognizing the ongoing decline in men’s health
Part 2: Ask the Experts: What problem in ophthalmology do you wish there was a solution for?
This series features experts in ophthalmology sharing their thoughts on the one unsolved challenge they wish there was a solution for.Video Transcript:Editor's note: The below transcript has been lightly edited for clarity.Joaquin DeRojas, MD:I wish that there was a solution for presbyopia in a way that exceeds what we currently have. We have excellent technology, and it's … [Read more...] about Part 2: Ask the Experts: What problem in ophthalmology do you wish there was a solution for?
AURN001 yields positive BCVA, corneal thickness outcomes in phase 1/2 trial
December 19, 2024 1 min read Key takeaways: For the primary endpoint, there was a dose-dependent response. The safety profile was favorable, with no ocular serious adverse events. AURN001, an allogeneic cell therapy candidate, achieved positive results in a phase 1/2 clinical trial for the treatment of corneal edema secondary to corneal endothelial dysfunction, … [Read more...] about AURN001 yields positive BCVA, corneal thickness outcomes in phase 1/2 trial